Medical Therapies to Reduce Delayed Graft Function and Improve Long-Term Graft Survival
نویسندگان
چکیده
منابع مشابه
Impact of delayed graft function on renal function and graft survival in deceased kidney transplantation.
OBJECTIVES To define the risk factors for delayed graft function and study the impact of such delays on renal function and long-term allograft survival in renal transplant recipients. DESIGN Single-centre retrospective study. SETTING Regional hospital, Hong Kong. PATIENTS Records of 118 Chinese renal transplant recipients from 1 July 1997 to 31 July 2005 were reviewed, and categorised int...
متن کاملDelayed Graft Function
Delayed graft function (DGF) is a common complication of renal transplantation. According to a clinical data analysis of 34,647 cases of cadaveric renal transplantation documented by the Renal Transplantation Registry of the United Network Sharing (UNOS), graft function did not recover instantly after transplantation and for ever in some cases; the 1-year rate of graft loss was up to 20% in cas...
متن کاملXenon Treatment Protects Against Cold Ischemia Associated Delayed Graft Function and Prolongs Graft Survival in Rats
Prolonged hypothermic storage causes ischemia-reperfusion injury (IRI) in the renal graft, which is considered to contribute to the occurrence of the delayed graft function (DGF) and chronic graft failure. Strategies are required to protect the graft and to prolong renal graft survival. We demonstrated that xenon exposure to human proximal tubular cells (HK-2) led to activation of range of prot...
متن کاملReduced graft function (with or without dialysis) vs immediate graft function--a comparison of long-term renal allograft survival.
BACKGROUND Delayed graft function (DGF) is a common complication in cadaveric kidney transplants affecting graft outcome. However, the incidence of DGF differs widely between centres as its definition is very variable. The purpose of this study was to define a parameter for DGF and immediate graft function (IGF) and to compare the graft outcome between these groups at our centre. METHODS The ...
متن کاملKidney and recipient weight incompatibility reduces long-term graft survival.
Long-term function of kidney allografts depends on multiple variables, one of which may be the compatibility in size between the graft and the recipient. Here, we assessed the long-term consequences of the ratio of the weight of the kidney to the weight of the recipient (KwRw ratio) in a multicenter cohort of 1189 patients who received a transplant between 1995 and 2006. The graft filtration ra...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2019
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.13961119